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腹腔镜活体供肾肾切除术对肾移植的经济影响。

The economic impact of laparoscopic living-donor nephrectomy on kidney transplantation.

作者信息

Mullins C Daniel, Thomas Simu K, Pradel Françoise G, Bartlett Stephen T

机构信息

Center on Drugs and Public Policy, The University of Maryland, Baltimore 21201, USA.

出版信息

Transplantation. 2003 May 15;75(9):1505-12. doi: 10.1097/01.TP.0000060280.28204.3C.

Abstract

BACKGROUND

End-stage renal disease accounts for $17.9 billion annually in direct medical costs in the United States. This study assessed the flow of expenditures from a Medicare perspective for laparoscopic donor nephrectomy compared with living and cadaveric transplantation and continued dialysis.

METHODS

This study involved a nonrandomized, retrospective investigation of patients with end-stage renal disease and charges using institutional and physician/supplier charges from the United States Renal Data System. The subjects were classified as laparoscopic living-donor transplant, living-donor transplant, cadaveric transplant, or dialysis patients. The first treatment date was set as the index date, and monthly charges were plotted from 12 months before and up to 48 months after the index date.

RESULTS

There were 230,769 dialysis patients and 44,063 transplant patients (181 laparoscopic living-donor, 11,466 living-donor, and 32,416 cadaveric). Monthly institutional charges were similar in the year preceding the index date, but they were higher for transplantation in the month after the index date and lower in subsequent periods. Two-year post-index cumulative charges were as follows: Monthly institutional charges were similar for the living-donor ($191,374) and laparoscopic living-donor ($192,053) transplant patients, followed by the cadaveric transplant ($229,449) and dialysis ($250,348) patients, whereas physician/supplier charges were highest for the laparoscopic living-donor transplant ($104,583) patients, followed by the dialysis ($73,730), cadaveric transplant ($70,369), and living-donor transplant ($65,897) patients. The break-even points for the living-donor, laparoscopic living-donor, and cadaveric transplant patients compared with the dialysis patients were 10, 14, and 18 months, respectively.

CONCLUSIONS

The laparoscopic procedure may be a beneficial alternative to the conventional open donor nephrectomy procedure and cadaveric transplantation, and it provides considerable benefits compared with dialysis.

摘要

背景

在美国,终末期肾病每年的直接医疗费用达179亿美元。本研究从医疗保险的角度评估了腹腔镜供体肾切除术与活体及尸体肾移植和持续透析相比的支出情况。

方法

本研究对终末期肾病患者进行了非随机回顾性调查,并使用美国肾脏数据系统中的机构及医生/供应商收费数据。研究对象分为腹腔镜活体供体移植组、活体供体移植组、尸体供体移植组或透析患者组。将首次治疗日期设为索引日期,并绘制索引日期前12个月至索引日期后48个月的每月收费情况。

结果

共有230,769例透析患者和44,063例移植患者(181例腹腔镜活体供体移植、11,466例活体供体移植和32,416例尸体供体移植)。索引日期前一年的每月机构收费相似,但索引日期后一个月移植的收费更高,随后各期则较低。索引日期后两年的累计收费如下:活体供体移植患者(191,374美元)和腹腔镜活体供体移植患者(192,053美元)的每月机构收费相似,其次是尸体供体移植患者(229,449美元)和透析患者(250,348美元),而医生/供应商收费最高的是腹腔镜活体供体移植患者(104,583美元),其次是透析患者(73,730美元)、尸体供体移植患者(70,369美元)和活体供体移植患者(65,897美元)。与透析患者相比,活体供体移植、腹腔镜活体供体移植和尸体供体移植患者的收支平衡点分别为10个月、14个月和18个月。

结论

腹腔镜手术可能是传统开放性供体肾切除术和尸体供体移植的有益替代方法,与透析相比具有显著优势。

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