Gürkan A, Kaçar S, Başak K, Varilsüha C, Karaca C
SSK Tepecik Hospital, Organ Transplantation Unit, Izmir, Turkey.
Transplant Proc. 2004 Jan-Feb;36(1):105-7. doi: 10.1016/j.transproceed.2003.11.064.
Laparoscopic donor nephrectomy is a new technique. For anatomical and technical reasons, many transplant centers restrict laparoscopic donor nephrectomy to kidneys with a single artery. However, we believe that with increased experience, laparoscopic donor nephrectomy in cases of multiple renal arteries does not affect donor or recipient outcomes. Among 115 living related renal transplantations performed between January 1996 and December 2002, 31 nephrectomies were performed via laparoscopy including eight with multiple arteries and 84 via an open approach, including nine with multiple arteries. The 17 patients with multiple arteries at the two procedures were compared in terms of donor and recipient outcomes. All the patients received the same immunosuppressive regimen. The demographic data were similar in the two groups. Mean durations of the donor operations (223 vs 247 minutes), side of nephrectomy (left/right, 5/4 vs 7/1), mean warm ischemia times (230 vs 432 seconds), mean serum creatinine levels at the end of 1 year follow-up, were statistically similar for the open versus the laparoscopy groups. Urological (11.1% vs 25%) and vascular complication rates (22.2% vs 25%), acute rejection rates (11.1% vs 12.5%) were also statistically similar for open versus laparoscopy groups, respectively. One-year patient and graft survival rates were 87.5% for both groups. Laparoscopic donor nephrectomy was as safe a procedure as open surgery even in the presence of multiple renal arteries in the hands of experienced transplants surgeons.
腹腔镜供肾切除术是一项新技术。由于解剖学和技术原因,许多移植中心将腹腔镜供肾切除术限制于单支动脉的肾脏。然而,我们认为随着经验的增加,多支肾动脉情况下的腹腔镜供肾切除术不会影响供者或受者的结局。在1996年1月至2002年12月期间进行的115例亲属活体肾移植中,31例肾切除术通过腹腔镜完成,其中8例为多支动脉,84例通过开放手术完成,其中9例为多支动脉。对这两种手术方式中17例有多支动脉的患者的供者和受者结局进行了比较。所有患者均接受相同的免疫抑制方案。两组的人口统计学数据相似。供者手术的平均时长(223分钟对247分钟)、肾切除的侧别(左/右,5/4对7/1)、平均热缺血时间(230秒对432秒)、随访1年末的平均血清肌酐水平,开放手术组与腹腔镜组在统计学上相似。泌尿外科并发症发生率(11.1%对25%)和血管并发症发生率(22.2%对25%)、急性排斥反应发生率(11.1%对12.5%),开放手术组与腹腔镜组分别在统计学上也相似。两组的1年患者和移植物存活率均为87.5%。即使在经验丰富的移植外科医生手中,对于有多支肾动脉的情况,腹腔镜供肾切除术与开放手术一样安全。