Cao Jin, Zhao Yan, Liu Jianwei, Xirao Ruodeng
Xiangya School of Medicine, Centro-South University, Changsha 410078, China.
Wei Sheng Yan Jiu. 2003 Mar;32(2):141-3.
To investigate health impact of brick-tea type fluorosis in adults, the total daily fluorine intake, environment fluorine level were determined, the average urinary fluorine content assay and bone X-ray examination were conducted, the clinical manifestations were observed in the brick-tea type bone fluorosis epidemiological study conducted in Naqu County, Tibet at September, 2001. One hundred and eleven adults aged at 30-78 year-old were enrolled. It was found that the fluorine level of drinking water in Naqu County was 0.10 +/- 0.03 mg/L, but the brick-tea water processed foods-zamba and buttered tea had fluorine content of 4.52 +/- 0.74 mg/kg and 3.21 +/- 0.65 mg/kg respectively. The adult daily fluorine intake reached 11.99 mg, among which 99% is originated from the brick-tea containing foods. Positive detection rate of fluorosis osteopathy was 89% and the X-ray film confirmed that the diagnosis rate was 83%. Degenerative arthropathy and ossification of the interosteal membrane, calcification of the tendon were the characteristics that indicated by both the positive signs and reogenological examination. The prevalence of osteosclerosis type (bone matrix increased) was 74%. It is suggested that there were even more severe health impact compared with those in the water type and coal combustion type fluorosis.
为调查成人砖茶型氟中毒对健康的影响,于2001年9月在西藏那曲县进行的砖茶型骨氟中毒流行病学研究中,测定了每日总氟摄入量、环境氟水平,进行了平均尿氟含量测定和骨骼X线检查,观察了临床表现。纳入了111名年龄在30 - 78岁的成年人。结果发现,那曲县饮用水氟含量为0.10±0.03mg/L,但砖茶加工食品糌粑和酥油茶的氟含量分别为4.52±0.74mg/kg和3.21±0.65mg/kg。成年人每日氟摄入量达11.99mg,其中99%来自含砖茶的食品。氟骨症阳性检出率为89%,X线片确诊率为83%。阳性体征和影像学检查均显示退行性关节病、骨间膜骨化、肌腱钙化是其特点。骨硬化型(骨基质增多)患病率为74%。提示其对健康的影响比饮水型和燃煤型氟中毒更为严重。