Ravaldi Claudia, Vannacci Alfredo, Ricca Valdo
Recenti Prog Med. 2003 Jun;94(6):267-70.
The death rate of anorexia nervosa (AN) patients is up to 30 times greater than that of age-matched normal women. Bradycardia, hypotension and mitral valve prolapse are cardiac abnormalities that can be frequently found in AN patients. Risk of death is substantially linked to QT prolongation, which could be due to hypokalemia (binge/purging type AN) or to a starvation-derived anatomical remodelling of the heart (restricting type AN). The principal risk factors are duration of illness > 10 years, chronic hypokalemia, plasmatic albumin chronically < 3.6 g/dl and absolute QT > or = 600 ms.
神经性厌食症（AN）患者的死亡率比年龄匹配的正常女性高出30倍。心动过缓、低血压和二尖瓣脱垂是AN患者中常见的心脏异常情况。死亡风险与QT间期延长密切相关，这可能是由于低钾血症（暴食/清除型AN）或饥饿导致的心脏解剖结构重塑（限制型AN）。主要风险因素包括病程>10年、慢性低钾血症、血浆白蛋白长期<3.6 g/dl以及绝对QT间期>或 = 600毫秒。
