Kosugi Michio, Hanawa Yasumasa, Momma Tetsuo, Saito Shiro, Hirose Shigemichi
Department of Urology, National Tokyo Medical Center.
Nihon Hinyokika Gakkai Zasshi. 2003 May;94(4):521-4. doi: 10.5980/jpnjurol1989.94.521.
Prostatic neuroendocrine (NE) carcinoma is a rare situation and the NE differentiation in the prostate adenocarcinoma appears to be characterized as poor prognosis, rapid tumor progression and the androgen-independent state, for which there is currently no successful therapy. We report two cases of NE differentiated prostatic carcinoma, which were diagnosed adenocarcinoma initially and the tumors progressed universally with NE differentiation during androgen suppression therapy.
前列腺神经内分泌（NE）癌是一种罕见的情况，前列腺腺癌中的NE分化似乎具有预后不良、肿瘤进展迅速和雄激素非依赖状态的特征，目前尚无成功的治疗方法。我们报告了两例NE分化型前列腺癌病例，这两例最初被诊断为腺癌，在雄激素抑制治疗期间肿瘤普遍出现NE分化并进展。
