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使用腹腔镜获取的供肾进行活体供肾肾移植后的受者结局

Recipient outcome following living donor kidney transplantation using kidneys procured laparoscopically.

作者信息

Reddy K Sudhakar, Mastrangelo Michael, D Johnston Thomas, Khan Taqi, Waid Thomas, McKeown Wade, Lucas Bruce, Ranjan Dinesh

机构信息

Departments of Surgery and Medicine, University of Kentucky, Lexington, KY 40536, USA.

出版信息

Clin Transplant. 2003;17 Suppl 9:44-7. doi: 10.1034/j.1399-0012.17.s9.8.x.

Abstract

BACKGROUND

Laparoscopic live donor nephrectomy is becoming increasingly popular as it has been shown to minimize donor morbidity, length of hospital stay and length of time to return to work. Initial experience suggested that kidneys procured laparoscopically had higher rates of delayed graft function and ureteric complications but with increasing experience, these complications have become less common.

METHODS

Retrospective chart review of all patients who underwent living donor kidney transplant using kidneys procured laparoscopically at our centre was performed. From the initiation of the laparoscopic donor nephrectomy programme at our institution in November 1998 until February 2002, we performed 71 living donor kidney transplants (69 kidneys procured laparoscopically and two procured by open donor nephrectomy after failed laparoscopic approach). Donor left kidney was used in all except in one patient. Mean duration of warm ischaemia time was 206 +/- 79 s.

RESULTS

The mean age of the recipients was 42 +/- 15 years (range 1-68) including five paediatric recipients (age < 18 years). There were 48 males and 23 females. Nine (13%) were retransplants (seven second transplants and one each of third and fourth transplants). Two patients died with functioning grafts and four patients lost the graft (three thrombosis, one anastomotic rupture). No patient developed ureteric complications. The incidence of delayed graft function (need for dialysis in the first week post-transplant) was 4%. Patient and graft survival rates (actual) were 97% and 91%, respectively. Mean length of hospital stay was 9 +/- 7 days (median 7 days).

CONCLUSIONS

Recipient outcome is not compromised and excellent results can be achieved with living donor kidney transplantation using laparoscopically procured kidneys.

摘要

背景

腹腔镜活体供肾切除术越来越受欢迎,因为它已被证明能将供者的发病率、住院时间和恢复工作的时间降至最低。初步经验表明,通过腹腔镜获取的肾脏发生移植肾功能延迟和输尿管并发症的几率较高,但随着经验的增加,这些并发症已变得不那么常见。

方法

对在我们中心接受使用腹腔镜获取的肾脏进行活体供肾移植的所有患者进行回顾性病历审查。从1998年11月我们机构启动腹腔镜供肾切除术项目到2002年2月,我们进行了71例活体供肾移植(69例通过腹腔镜获取肾脏,2例在腹腔镜手术失败后通过开放供肾切除术获取)。除1例患者外,均使用供者的左肾。平均热缺血时间为206±79秒。

结果

受者的平均年龄为42±15岁(范围1 - 68岁),包括5名儿童受者(年龄<18岁)。有48名男性和23名女性。9例(13%)为再次移植(7例第二次移植,第三和第四次移植各1例)。2例患者在移植肾功能良好时死亡,4例患者移植肾失功(3例血栓形成,1例吻合口破裂)。无患者发生输尿管并发症。移植肾功能延迟(移植后第一周需要透析)的发生率为4%。患者和移植肾的实际生存率分别为97%和91%。平均住院时间为9±7天(中位数7天)。

结论

使用腹腔镜获取的肾脏进行活体供肾移植不会影响受者的预后,并且可以取得优异的结果。

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