Dutcher Susan K
Department of Genetics, Washington University School of Medicine, 660 S. Euclid Ave, St. Louis, MO 63110, USA.
Traffic. 2003 Jul;4(7):443-51. doi: 10.1034/j.1600-0854.2003.00104.x.
In eukaryotic cells, basal bodies and their structural equivalents, centrioles, play essential roles. They are needed for the assembly of flagella or cilia as well as for cell division. Chlamydomonas reinhardtii provides an excellent model organism for the study of the basal body and centrioles. Genes for two new members of the tubulin superfamily are needed for basal body/centriole duplication. In addition, other genes that play roles in the duplication and segregation of basal bodies are discussed.
在真核细胞中,基体及其结构等同物中心粒发挥着重要作用。鞭毛或纤毛的组装以及细胞分裂都需要它们。莱茵衣藻为研究基体和中心粒提供了一个出色的模式生物。基体/中心粒复制需要微管蛋白超家族两个新成员的基因。此外,还讨论了在基体复制和分离中发挥作用的其他基因。