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[重组干扰素治疗肾病综合征型肾小球肾炎患者的临床实验室动态变化]

[The clinico-laboratory dynamics in the reaferon treatment of glomerulonephritis patients with the nephrotic syndrome].

作者信息

Shishkin A N, Sosunov A V, Romanova V I, Korneeva E P, Orlov V A

出版信息

Ter Arkh. 1992;64(6):29-32.

PMID:1279826
Abstract

Overall 40 chronic glomerulonephritis patients with nephrotic syndrome were treated by reaferon. All the patients underwent clinical and laboratory examinations and nephric biopsy. As a result of the treatment, all the patients demonstrated an increase of the level of glomerular filtration, stabilization of protein and lipid metabolism along with the lowering of diurnal proteinuria. Reaferon exerted a beneficial effect on cellular factors of immunity. In some cases, the use of reaferon can be a definite alternative of the conventional treatment methods.

摘要

总共40例慢性肾小球肾炎肾病综合征患者接受了干扰素治疗。所有患者均接受了临床和实验室检查以及肾活检。治疗结果显示,所有患者的肾小球滤过水平均有所提高,蛋白质和脂质代谢稳定,同时日间蛋白尿减少。干扰素对免疫细胞因子产生了有益影响。在某些情况下,使用干扰素可以成为传统治疗方法的明确替代方案。

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