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血液透析后后部缺血性视神经病变

Posterior ischemic optic neuropathy after hemodialysis.

作者信息

Buono Lawrence M, Foroozan Rod, Savino Peter J, Danesh-Meyer Helen V, Stanescu Dinu

机构信息

Neuro-Ophthalmology Service, Wills Eye Hospital, Thomas Jefferson Medical College, Philadelphia, Pennsylvania, USA.

出版信息

Ophthalmology. 2003 Jun;110(6):1216-8. doi: 10.1016/S0161-6420(03)00257-4.

Abstract

PURPOSE

To report a case of visual loss from posterior ischemic optic neuropathy (PION) after hemodialysis.

DESIGN

Observational case report.

METHODS

Neuro-ophthalmic examination, neuro-imaging including computed tomography (CT) scan, magnetic resonance imaging (MRI) of the head and orbits, and magnetic resonance angiography (MRA) of the neck and cerebral vasculature, as well as electrophysiologic testing including electroretinogram (ERG) and visually evoked response (VER) were performed.

RESULTS

Acute onset of painless bilateral no light perception vision with absent pupillary response to light and normal funduscopic examination occurred shortly after completion of hemodialysis. Computed tomography scan and MRA results were normal. Magnetic resonance imaging scan showed small vessel ischemic white matter changes. Electroretinogram results were normal and the VER was unrecordable.

CONCLUSIONS

Visual loss after hemodialysis is a rare complication and is associated with anemia and hypotensive events. The visual loss is usually a result of anterior ischemic optic neuropathy. We were unable to find another instance in the literature of visual loss after hemodialysis resulting from PION.

摘要

目的

报告一例血液透析后发生后部缺血性视神经病变(PION)导致视力丧失的病例。

设计

观察性病例报告。

方法

进行了神经眼科检查、神经影像学检查,包括计算机断层扫描(CT)、头部和眼眶的磁共振成像(MRI)以及颈部和脑血管系统的磁共振血管造影(MRA),还进行了电生理测试,包括视网膜电图(ERG)和视觉诱发电位(VER)。

结果

血液透析结束后不久,患者出现急性无痛性双侧无光感视力丧失,对光无瞳孔反应,眼底检查正常。CT扫描和MRA结果正常。MRI扫描显示小血管缺血性白质改变。ERG结果正常,VER无法记录。

结论

血液透析后视力丧失是一种罕见的并发症,与贫血和低血压事件有关。视力丧失通常是前部缺血性视神经病变的结果。我们在文献中未能找到另一例因PION导致血液透析后视力丧失的病例。

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