Hynes Michael J
Department of Genetics, University of Melbourne, Parkville, Victoria 3010, Australia.
Genome Biol. 2003;4(6):217. doi: 10.1186/gb-2003-4-6-217. Epub 2003 May 28.
The filamentous fungus Neurospora crassa, which has played an important role in the development of modern genetics, has several unique genome-defense mechanisms, including a process called repeat-induced point mutation. The draft genome sequence has revealed several unusual features, which suggest that the evolution of N. crassa has been greatly influenced by these defense mechanisms.
丝状真菌粗糙脉孢菌在现代遗传学发展中发挥了重要作用,它具有多种独特的基因组防御机制,包括一种称为重复序列诱导点突变的过程。基因组草图序列揭示了几个不同寻常的特征,这表明粗糙脉孢菌的进化受到了这些防御机制的极大影响。