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粗糙脉孢菌基因组开启了丝状真菌的世界。

The Neurospora crassa genome opens up the world of filamentous fungi.

作者信息

Hynes Michael J

机构信息

Department of Genetics, University of Melbourne, Parkville, Victoria 3010, Australia.

出版信息

Genome Biol. 2003;4(6):217. doi: 10.1186/gb-2003-4-6-217. Epub 2003 May 28.

Abstract

The filamentous fungus Neurospora crassa, which has played an important role in the development of modern genetics, has several unique genome-defense mechanisms, including a process called repeat-induced point mutation. The draft genome sequence has revealed several unusual features, which suggest that the evolution of N. crassa has been greatly influenced by these defense mechanisms.

摘要

丝状真菌粗糙脉孢菌在现代遗传学发展中发挥了重要作用,它具有多种独特的基因组防御机制,包括一种称为重复序列诱导点突变的过程。基因组草图序列揭示了几个不同寻常的特征,这表明粗糙脉孢菌的进化受到了这些防御机制的极大影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5507/193610/9741b9ceaa99/gb-2003-4-6-217-1.jpg

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