Vítová Z, Srajer J
Physiol Bohemoslov. 1975;24(6):535-42.
Frequency-power spectra of the EEG evoked by repeptitive photic stimulation and of the background EEG were studied during childhood in 43 awake subjects aged between 2 months and 14 years. EEG activity was recorded from the middle parieto-occipital region with the aid of a 1-channel analyzer Lysograf-Alvar, analysing 16 frequencies in the range from 2 to 28 c/sec. The responsiveness of the central nervous system to flickering light improved in the course of childhood in parallel with the significant decline of delta activity and with the prominent increase of alpha intensity in the resting EEG. The 4th month of life appeared to be a marked turning point in the development of evoked and background EEGs. From that age, the bioelectric power at the flash rate corresponding to photic "driving" began to increase together with the highest and optimal driving frequencies. The flash rate, at which evoked potentials changed into the "driven" rhythm, also shifted towards higher frequencies. Subsequently, the amount of energy in the resting EEG increased significantly within the theta, alpha and beta bands and, on the contrary, a prominent decline was observed in the delta range. Marked ontogenetic changes at this age closely coincided with the rapid development of exogenous fibres in the occipital cortex, including the thalamo-cortical conncetions, and fibres of the neuropil in cortical layer I, which might play an important role in the genesis of background and "driven" in the occipital region.
在43名年龄在2个月至14岁之间的清醒儿童中，研究了重复光刺激诱发的脑电图（EEG）的频率-功率谱以及背景脑电图。借助Lysograf-Alvar单通道分析仪，从顶枕中部区域记录EEG活动，该分析仪可分析2至28赫兹范围内的16个频率。在儿童期，中枢神经系统对闪烁光的反应性随着δ活动的显著下降以及静息脑电图中α强度的显著增加而改善。出生后第4个月似乎是诱发脑电图和背景脑电图发展的一个明显转折点。从那个年龄开始，与光“驱动”相对应的闪光频率下的生物电功率开始增加，同时最高和最佳驱动频率也增加。诱发电位转变为“驱动”节律的闪光频率也向更高频率移动。随后，静息脑电图中θ、α和β频段的能量显著增加，相反，δ频段则出现明显下降。这个年龄的明显个体发育变化与枕叶皮质中外源性纤维的快速发育密切相关，包括丘脑-皮质连接以及皮质I层神经毡的纤维，这些纤维可能在枕叶区域背景和“驱动”脑电图的发生中起重要作用。
