Honoré Charles, Detry Olivier, De Roover Arnaud, Meurisse Michel, Honoré Pierre
Department of Liver Surgery and Transplantation, University of Liège, CHU Sart Tilman B35, 4000, Liège, Belgium.
Transpl Int. 2003 Sep;16(9):692-3. doi: 10.1007/s00147-003-0605-3. Epub 2003 Jun 12.
Because of dismal mid-term and long-term results, secondary liver cancer is considered an absolute contra-indication to cadaveric liver transplantation, with the relative exception of metastases of symptomatic neuro-endocrine cancers. The authors present in this report the case of a patient who has been enjoying 10 years of cancer-free survival after liver transplantation as rescue therapy for acute liver failure after liver resection for isolated hepatic metastasis of colon adenocarcinoma. This case shows that in some highly selected cases, liver transplantation may be curative in patients with liver metastases of colon carcinoma.
由于中期和长期预后不佳,继发性肝癌被视为尸体肝移植的绝对禁忌证,但有症状的神经内分泌癌转移相对除外。作者在本报告中介绍了一例患者,该患者在因孤立性肝转移行肝切除术后发生急性肝衰竭,接受肝移植作为挽救治疗后已无癌生存10年。该病例表明,在某些经过严格筛选的病例中,肝移植可能治愈结肠癌肝转移患者。