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入射剂量测量:一种简单可靠的技术。

Entrance dose measurement: a simple and reliable technique.

作者信息

Banjade D P, Raj T Aloysius, Ng B S, Xavier S, Tajuddin A A, Shukri A

机构信息

School of Physics, Universiti Sains Malaysia, Penang, Malaysia.

出版信息

Med Dosim. 2003 Summer;28(2):73-8. doi: 10.1016/S0958-3947(02)00236-4.

Abstract

Verification of tumor dose for patients undergoing external beam radiotherapy is an important part of quality assurance programs in radiation oncology. Among the various methods available, entrance dose in vivo is one reliable method used to verify the tumor dose delivered to a patient. In this work, entrance dose measurements using LiF:Mg;Ti and LiF:Mg;Cu;P thermoluminescent dosimeters (TLDs) without buildup cap was carried out. The TLDs were calibrated at the surface of a water equivalent phantom against the maximum dose, using 6- and 10-MV photon and 9-MeV electron beams. The calibration geometry was such that the TLDs were placed on the surface of the "solid-water" phantom and a calibrated ionization chamber was positioned inside the phantom at calibration depth. The calibrated TLDs were then utilized to measure the entrance dose during the treatment of actual patients. Measurements were also carried out in the same phantom simultaneously to check the stability of the system. The dose measured in the phantom using the TLDs calibrated for entrance dose to 6-and 10-MV photon beams was found to be close to the dose determined by the treatment planning system (TPS) with discrepancies of not more than 4.1% (mean 1.3%). Consequently, the measured entrance dose during dose delivery to the actual patients with a prescribed geometry was found to be compatible with a maximum discrepancy of 5.7% (mean 2.2%) when comparison was made with the dose determined by the TPS. Likewise, the measured entrance dose for electron beams in the phantom and in actual patients using the calibrated TLDs were also found to be close, with maximum discrepancies of 3.2% (mean 2.0%) and 4.8% (mean 2.3%), respectively. Careful implementation of this technique provides vital information with an ability to confidently accept treatment algorithms derived by the TPS or to re-evaluate the parameters when necessary.

摘要

对外照射放疗患者的肿瘤剂量进行验证是放射肿瘤学质量保证计划的重要组成部分。在现有的各种方法中,体内入射剂量是用于验证给予患者的肿瘤剂量的一种可靠方法。在这项工作中,使用未加建成帽的LiF:Mg;Ti和LiF:Mg;Cu;P热释光剂量计(TLD)进行了入射剂量测量。TLD在水等效体模表面针对最大剂量进行校准,使用6兆伏和10兆伏光子束以及9兆伏电子束。校准几何条件是将TLD放置在“固体水”体模表面,在校准深度将校准电离室放置在体模内部。然后将校准后的TLD用于测量实际患者治疗期间的入射剂量。同时也在同一体模中进行测量以检查系统的稳定性。使用针对6兆伏和10兆伏光子束入射剂量校准的TLD在体模中测量的剂量被发现与治疗计划系统(TPS)确定的剂量接近,差异不超过4.1%(平均1.3%)。因此,当与TPS确定的剂量进行比较时,发现在以规定几何条件向实际患者进行剂量输送期间测量的入射剂量与最大差异5.7%(平均2.2%)兼容。同样,使用校准后的TLD在体模和实际患者中测量的电子束入射剂量也被发现接近,最大差异分别为3.2%(平均2.0%)和4.8%(平均2.3%)。仔细实施该技术可提供重要信息,使人们能够有信心接受TPS得出的治疗算法,或在必要时重新评估参数。

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