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用于高能光子束中皮肤剂量测定的超薄热释光剂量计

Ultra-thin TLDs for skin dose determination in high energy photon beams.

作者信息

Stathakis S, Li J S, Paskalev K, Yang J, Wang L, Ma C-M

机构信息

Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.

出版信息

Phys Med Biol. 2006 Jul 21;51(14):3549-67. doi: 10.1088/0031-9155/51/14/018. Epub 2006 Jul 6.

Abstract

Estimation of surface dose is very important for patients undergoing radiation therapy. In this work we investigate the dose at the surface of a water phantom and at a depth of 0.007 cm, the practical reference depth for skin as recommended by ICRP and ICRU, with ultra-thin TLDs and Monte Carlo calculations. The calculations and measurements were carried out for fields ranging from 5 x 5 cm2 to 20 x 20 cm2 for 6 MV, 10 MV and 18 MV photon beams. The variation of the surface dose with angle of incidence and field size was investigated. Also, the exit dose was computed and measured for the same fields and angles of incidence. The dose at the ICRU reference depth was computed. Good agreement (+/-5%) was achieved between measurements and calculations. The surface dose at the entrance increased with the angle of incidence and/or the field size. The exit dose decreased with the angle of incidence but it increased with field size. The dose at the surface of the patient is mostly dependent on the beam energy, modality and beam obliquity rather than the field size and field separation. By correlating TLD measurements with Monte Carlo calculations, we were able to predict the dose at the skin surface with good accuracy. Knowing the dose received at the surface of the patient can lead to prediction of skin reactions helping with the design of new treatment techniques and alternative dose fractionation schemes.

摘要

对于接受放射治疗的患者而言,表面剂量的估算非常重要。在本研究中,我们使用超薄热释光剂量仪(TLD)并通过蒙特卡罗计算,来研究水模体表面以及深度为0.007厘米(这是国际辐射防护委员会(ICRP)和国际辐射单位与测量委员会(ICRU)推荐的皮肤实际参考深度)处的剂量。针对6兆伏、10兆伏和18兆伏的光子束,对面积从5×5平方厘米到20×20平方厘米的射野进行了计算和测量。研究了表面剂量随入射角和射野大小的变化情况。此外,还针对相同的射野和入射角计算并测量了出射剂量。计算了ICRU参考深度处的剂量。测量值与计算值之间达成了良好的一致性(±5%)。入口处的表面剂量随入射角和/或射野大小的增加而增加。出射剂量随入射角减小,但随射野大小增加。患者表面的剂量主要取决于束流能量、模式和束流倾斜度,而非射野大小和射野间距。通过将TLD测量结果与蒙特卡罗计算相关联,我们能够较为准确地预测皮肤表面的剂量。了解患者表面所接受的剂量有助于预测皮肤反应,从而辅助新治疗技术和替代剂量分割方案的设计。

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