Graham P H, Browne L, Cox H, Graham J
Cancer Care Centre, St George Hospital, Gray St, Kogarah, Australia, 2217.
J Clin Oncol. 2003 Jun 15;21(12):2372-6. doi: 10.1200/JCO.2003.10.126.
To determine whether the inhalation of aromatherapy during radiotherapy reduces anxiety.
Three hundred thirteen patients undergoing radiotherapy were randomly assigned to receive either carrier oil with fractionated oils, carrier oil only, or pure essential oils of lavender, bergamot, and cedarwood administered by inhalation concurrently with radiation treatment. Patients underwent assessment by the Hospital Anxiety and Depression Scale (HADS) and the Somatic and Psychological Health Report (SPHERE) at baseline and at treatment completion.
There were no significant differences in HADS depression or SPHERE scores between the randomly assigned groups. However, HADS anxiety scores were significantly lower at treatment completion in the carrier oil only group compared with either of the fragrant arms (P =.04).
Aromatherapy, as administered in this study, is not beneficial.
确定放疗期间吸入芳香疗法是否能减轻焦虑。
313名接受放疗的患者被随机分配，分别接受含有分馏油的载体油、仅载体油，或在放疗同时通过吸入给予薰衣草、佛手柑和雪松木纯精油。患者在基线和治疗结束时通过医院焦虑抑郁量表（HADS）和躯体与心理健康报告（SPHERE）进行评估。
随机分组的各组之间，HADS抑郁评分或SPHERE评分无显著差异。然而，仅载体油组在治疗结束时的HADS焦虑评分显著低于任何一个芳香疗法组（P = 0.04）。
本研究中所采用的芳香疗法并无益处。
