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[伴有横纹肌样转化的脑膜瘤:病例报告]

[Meningioma with rhabdoid transformation: case report].

作者信息

da Costa Leodante Batista, de Morais Josaphat Vilela

机构信息

Fundação Benjamin Guimarães, Belo Horizonte MG, Brasil.

出版信息

Arq Neuropsiquiatr. 2003 Jun;61(2A):277-80. doi: 10.1590/s0004-282x2003000200023. Epub 2003 Jun 9.

Abstract

Meningiomas represent aproximatelly 30% of all intracranial tumors in autopsy studies. With an incidence of 2.3 per 100000, they are considered commom tumors in clinical practice. Twenty percent of the all intracranial tumors diagnosed in vivo are meningiomas. Most of these lesions are benign and the prognosis is intimatelly related to acessibility and ressectability of the lesion. Malignant meningiomas are rare lesions, representing between 1 to 11% of all meningiomas, varying with the definition of pathological criteria for malignancy used, and are categorized in atypical or malignant. Only recently rhabdoid transformation of meningiomas have been reported. We present a case of an extremelly aggressive rhabdoid meningioma in a 56 year-old woman. The tumor was surgically removed twice, with a lethal outcome due to local recurrence, despite maximum radiation and quimiotherapy, six months after the initial presentation.

摘要

尸检研究表明,脑膜瘤约占所有颅内肿瘤的30%。其发病率为每10万人中有2.3例,在临床实践中被视为常见肿瘤。在活体诊断的所有颅内肿瘤中,20%为脑膜瘤。这些病变大多为良性,预后与病变的可及性和可切除性密切相关。恶性脑膜瘤是罕见病变,占所有脑膜瘤的1%至11%,因所采用的恶性病理标准定义不同而有所差异,可分为非典型或恶性。脑膜瘤的横纹肌样转化直到最近才被报道。我们报告一例56岁女性的极具侵袭性的横纹肌样脑膜瘤病例。尽管在首次就诊后6个月进行了最大剂量的放疗和化疗,但肿瘤仍两次手术切除,最终因局部复发导致致命后果。

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