Urabe Akio
Division of Hematology, NTT Kanto Medical Center.
Nihon Rinsho. 2003 Jun;61(6):949-53.
Bone marrow suppression is one of the most popular side effects of cancer chemotherapy. Bone marrow suppression includes neutropenia, anemia and thrombocytopenia. Clinical application of cytokine is useful in the treatment of bone marrow suppression due to cancer chemotherapy. Granulocyte colony-stimulating factor(G-CSF) is useful in the treatment of neutropenia. Erythropoietin(EPO) is useful is the treatment of anemia. However, EPO is not widely used in Japan yet. Clinical application of varions cytokines will bring forth much improvement in the treatment of bone marrow suppression due to cancer chemotherapy.
骨髓抑制是癌症化疗最常见的副作用之一。骨髓抑制包括中性粒细胞减少、贫血和血小板减少。细胞因子的临床应用对治疗癌症化疗引起的骨髓抑制很有用。粒细胞集落刺激因子(G-CSF)对治疗中性粒细胞减少有用。促红细胞生成素(EPO)对治疗贫血有用。然而,EPO在日本尚未广泛使用。各种细胞因子的临床应用将在癌症化疗引起的骨髓抑制治疗方面带来很大改善。