Chakravarty A
Division of Neurology, Vivekananda Institute of Medical Sciences, Calcutta.
Acta Neurol Scand. 2003 Jul;108(1):60-5. doi: 10.1034/j.1600-0404.2003.00039.x.
In three patients with infantile hemiplegia syndrome, MR imaging done later in life showed significant volume loss in the cerebellar hemisphere contralateral to the side of the affected cerebrum in two and ipsilateral in one. By comparison, the cerebellar volume loss seemed to correlate with the degree of volume loss in the contralateral cerebral hemispheres in two patients. These observations provide morphological evidence of the phenomenon of crossed and uncrossed/ipsilateral cerebral cerebellar diaschisis (CCD and ICD). Functional neuroimaging studies in support of the concept of CCD and ICD have been critically reviewed in the light of the morphological changes demonstrated in the cases cited herein.
在三名患有小儿偏瘫综合征的患者中,成年后进行的磁共振成像显示,两名患者患侧大脑对侧的小脑半球出现明显体积缩小,一名患者为同侧小脑半球体积缩小。相比之下,两名患者的小脑体积缩小似乎与对侧大脑半球的体积缩小程度相关。这些观察结果为交叉性和非交叉性/同侧性大脑小脑远隔性机能障碍(CCD和ICD)现象提供了形态学证据。鉴于本文引用病例中所显示的形态学变化,对支持CCD和ICD概念的功能性神经影像学研究进行了严格审查。