Callanan D, Gass J D
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL 33101.
Ophthalmology. 1992 Nov;99(11):1678-85. doi: 10.1016/s0161-6420(92)31755-5.
Several recent articles have described syndromes in which there is enlargement of the blind spot associated with retinal lesions. These have included the multiple evanescent white dot syndrome, acute macular neuroretinopathy, acute idiopathic blind spot enlargement syndrome, and multifocal choroiditis or pseudo presumed ocular histoplasmosis syndrome (pseudo POHS).
The authors reviewed the records of seven patients in whom signs and symptoms of acute enlargement of the blind spot and pseudo POHS developed.
All seven patients had photopsia accompanying enlargement of the blind spot during their illness. Four had transient white spots as seen in the multiple evanescent white dot syndrome. All presented with or developed chorioretinal scars or neovascularization similar to that seen in multifocal choroiditis or pseudo POHS. In four of the seven patients, POHS-like scars developed only in the eye that was symptomatic with blind spot enlargement and photopsia. Five of the 7 had visual acuity of 20/25 or better at the last follow-up.
It would appear that there is an overlap in the clinical findings of all of these syndromes and that there may be a common link in their etiology.
最近有几篇文章描述了与视网膜病变相关的盲点扩大综合征。这些综合征包括多发性一过性白点综合征、急性黄斑神经视网膜病变、急性特发性盲点扩大综合征以及多灶性脉络膜炎或假性眼组织胞浆菌病综合征（假性POHS）。
作者回顾了7例出现盲点急性扩大和假性POHS体征及症状患者的病历。
所有7例患者在患病期间盲点扩大时均伴有闪光感。4例出现了多发性一过性白点综合征中所见的一过性白点。所有患者均出现或发展为脉络膜视网膜瘢痕或新生血管，类似于多灶性脉络膜炎或假性POHS中所见。在7例患者中的4例中，仅在出现盲点扩大和闪光感症状的眼中出现了POHS样瘢痕。7例患者中有5例在最后一次随访时视力达到20/25或更好。
所有这些综合征的临床发现似乎存在重叠，并且它们的病因可能存在共同联系。
