Kim Na Rae, Sung Chang Ohk, Han Joungho
Department of Pathology, Kangnam General Hospital Public Corporation, Seoul, Korea.
J Korean Med Sci. 2003 Jun;18(3):452-4. doi: 10.3346/jkms.2003.18.3.452.
Scrotal leiomyomas with atypical bizarre nuclei are rare, which might be misdiagnosed as malignant tumor. We describe a case of scrotal bizarre leiomyoma in a 65-yr-old man. The tumor was a 1 cm-sized, well circumscribed, oval mass arising from the tunica dartos muscle. Histologically, it was formed by whorling bundles of fusiform cells with occasional atypical, pleomorphic nuclei and pseudo-inclusions. Mitosis was not found. Although morphologically atypical, scrotal bizarre leiomyomas take on a biologic behavior not different from that of conventional leiomyoma, they should be distinguished from leiomyosarcoma to avoid unnecessary treatment.
伴有非典型奇异核的阴囊平滑肌瘤很罕见,可能会被误诊为恶性肿瘤。我们描述一例65岁男性阴囊奇异平滑肌瘤病例。肿瘤为1厘米大小,边界清楚,椭圆形肿块,起源于肉膜肌。组织学上,它由梭形细胞的漩涡状束组成,偶尔有非典型、多形性核及假包涵体。未发现有丝分裂。虽然形态学上不典型,但阴囊奇异平滑肌瘤的生物学行为与传统平滑肌瘤无异,应与平滑肌肉瘤相鉴别以避免不必要的治疗。