Fatunde O J, Scott-Emuakpor A B
Department of Child Health, University of Benin Teaching Hospital, Nigeria.
Trop Geogr Med. 1992 Jul;44(3):264-6.
The relationship of foetal haemoglobin (HbF) to several clinical and haematological parameters in 86 children aged 5 to 16 years who had sickle cell anaemia (SCA) has been examined. The mean HbF level was 6.8 +/- 3.6%. Higher HbF values were significantly associated with fewer blood transfusions, fewer hospital admissions and higher rate of hepatomegaly. A trend for children with higher HbF levels to have better physical development and a more normal haemogram was also noted though this was not statistically significant.
对86名年龄在5至16岁的镰状细胞贫血（SCA）患儿的胎儿血红蛋白（HbF）与若干临床和血液学参数之间的关系进行了研究。HbF平均水平为6.8 +/- 3.6%。较高的HbF值与较少的输血次数、较少的住院次数以及较高的肝肿大发生率显著相关。尽管未达到统计学显著性，但也注意到HbF水平较高的儿童有身体发育更好和血常规更正常的趋势。
