Kucukaksu Deniz Suha, Sener Erol, Undar Akif, Noon George P, Tasdemir Oguz
Cardiovascular Surgery Clinic at Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey.
Tex Heart Inst J. 2003;30(2):114-20.
Mechanical bridging to cardiac transplantation with a ventricular assist device may be a life-saving procedure for patients with end-stage heart failure. Here we report our 3 cases of patients implanted with the MicroMed DeBakey VAD (ventricular assist device). Three male patients, aged 37, 41, and 40, had end-stage left heart failure due to idiopathic cardiomyopathy and were listed for cardiac transplantation. They had progressive hemodynamic deterioration. Although Patient 1 underwent surgery, after device implantation, for bowel necrosis caused by thromboemboli of unknown origin, heart transplantation was performed 70 days after implantation. Pump thrombosis occurred in Patient 2 on the 120th day. Outflow graft ligation was performed because the patient refused a pump exchange. This patient died on the 25th day after ligation and the 145th day after ventricular assist device implantation. A heparin-coated version of the device was implanted in Patient 3, whose preoperative profound biventricular failure had been improved by inotropic medication and intra-aortic balloon pump support. Successful heart transplantation was performed 161 days after implantation. These are the 1st implantations of a left ventricular assist device in Turkey. From these cases, we have learned that the DeBakey VAD supplies adequate blood flow during the bridging period and, due to its simplicity, portability, and low infection rate, enables discharge of the patient from the hospital. However, preoperative psychological evaluation and postoperative psychological support are important for a successful bridging procedure, as is close observation of coagulation and of pump operation.
使用心室辅助装置进行机械搭桥以实现心脏移植,对于终末期心力衰竭患者可能是一种挽救生命的手术。在此,我们报告3例植入MicroMed DeBakey VAD(心室辅助装置)的患者情况。3例男性患者,年龄分别为37岁、41岁和40岁,因特发性心肌病导致终末期左心衰竭,被列入心脏移植名单。他们的血流动力学状况逐渐恶化。患者1在装置植入后因不明原因的血栓栓塞导致肠坏死而接受手术,植入后70天进行了心脏移植。患者2在第120天发生泵血栓形成。由于患者拒绝更换泵,进行了流出道移植物结扎。该患者在结扎后第25天、心室辅助装置植入后第145天死亡。患者3植入了肝素涂层版本的装置,其术前严重的双心室衰竭通过使用正性肌力药物和主动脉内球囊泵支持得到改善。植入后161天成功进行了心脏移植。这些是土耳其首次植入左心室辅助装置的病例。从这些病例中我们了解到,DeBakey VAD在搭桥期间能提供足够的血流,并且由于其简单、便携和感染率低,可使患者出院。然而,术前心理评估和术后心理支持对于成功的搭桥手术很重要,密切观察凝血情况和泵的运行情况也同样重要。