表现为无疱疹性带状疱疹、带状疱疹性轻瘫和脊髓病的慢性活动性水痘-带状疱疹病毒感染。

Chronic active VZV infection manifesting as zoster sine herpete, zoster paresis and myelopathy.

作者信息

Morita Y, Osaki Y, Doi Y, Forghani B, Gilden D H

机构信息

Department of Medicine and Geriatrics, Kochi Medical School, Kochi, Japan.

出版信息

J Neurol Sci. 2003 Aug 15;212(1-2):7-9. doi: 10.1016/s0022-510x(03)00081-9.

DOI:10.1016/s0022-510x(03)00081-9

PMID:12809993

Abstract

After lumbar-distribution zoster, an HTLV-1-seropositive woman developed chronic radicular sacral-distribution pain (zoster sine herpete), cervical-distribution zoster paresis and thoracic-distribution myelopathy. Detection of anti-varicella zoster virus (VZV) IgM and VZV IgG antibody in cerebrospinal fluid (CSF), with reduced serum/CSF ratios of anti-VZV IgG compared to normal serum/CSF ratios for albumin and total IgG, proved that VZV caused the protracted neurological complications. Diagnosis by antibody testing led to aggressive antiviral treatment and a favorable outcome.

摘要

一名HTLV-1血清反应阳性的女性在发生腰部带状疱疹后，出现了慢性骶部放射性疼痛（无疱疹性带状疱疹）、颈部带状疱疹性轻瘫和胸部脊髓病。脑脊液（CSF）中抗水痘带状疱疹病毒（VZV）IgM和VZV IgG抗体检测显示，与白蛋白和总IgG的正常血清/脑脊液比值相比，抗VZV IgG的血清/脑脊液比值降低，这证明VZV导致了迁延性神经并发症。通过抗体检测进行诊断后，积极的抗病毒治疗取得了良好效果。