Chang Yukyung, Lee Seokhwa, Lee Minho, Lee Ohyoung
Department of Food and Nutrition, College of Human Ecology, Hanyang University, Seoul, Korea.
Asia Pac J Clin Nutr. 2003;12(2):203-8.
This descriptive cross-sectional study aimed to investigate whether malnutrition occurs in outpatients with liver cirrhosis, and to compare the nutritional status of patients with alcoholic and viral liver cirrhosis using a variety of objective measures. This study also aimed to provide useful information about nutritional education and nutritional therapies for medical teams and patients with liver cirrhosis. Sixty-six Korean men between the ages of 30 and 69 with liver cirrhosis (24 alcohol-related and 42 virus-related) were recruited from the Internal Medicine Centres, Hanyang University Hospital, Seoul, Korea. The results showed that patients with alcoholic liver cirrhosis (ALC) were significantly lower in socio-economic status than patients with viral liver cirrhosis (VLC) (P<0.05). The energy intakes (excluding alcohol-derived energy) were 1448kcal and 1769kcal in the ALC and the VLC groups, respectively (P<0.05). As well, vitamin C intake was found to be higher in the VLC group than the ALC group, yet still more than 125% of the RDA for both groups (P<0.05). Among nutritional indices, only the TSF thickness showed interaction with the aetiology and the severity of the cirrhosis (P<0.05). Thus, these findings indicate that outpatients with liver cirrhosis in this study, particularly those with alcoholic liver cirrhosis, consumed a lower energy intake than suggested, but may not have been in a status of malnutrition. Body fat is more affected than other nutritional parameters in patients with liver cirrhosis.
这项描述性横断面研究旨在调查肝硬化门诊患者是否存在营养不良,并使用多种客观指标比较酒精性和病毒性肝硬化患者的营养状况。本研究还旨在为医疗团队和肝硬化患者提供有关营养教育和营养治疗的有用信息。从韩国首尔汉阳大学医院内科中心招募了66名年龄在30至69岁之间的韩国男性肝硬化患者(24例酒精相关性肝硬化和42例病毒相关性肝硬化)。结果显示,酒精性肝硬化(ALC)患者的社会经济地位显著低于病毒性肝硬化(VLC)患者(P<0.05)。ALC组和VLC组的能量摄入量(不包括酒精衍生能量)分别为1448千卡和1769千卡(P<0.05)。此外,发现VLC组的维生素C摄入量高于ALC组,但两组均仍超过推荐膳食摄入量(RDA)的125%(P<0.05)。在营养指标中,只有肱三头肌皮褶厚度(TSF)显示出与肝硬化病因和严重程度存在相互作用(P<0.05)。因此,这些研究结果表明,本研究中的肝硬化门诊患者,尤其是酒精性肝硬化患者,能量摄入量低于建议值,但可能不存在营养不良状况。在肝硬化患者中,身体脂肪比其他营养参数受影响更大。