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[酒精性肝病患者的营养状况:七十年代与当前情况的比较]

[Nutritional status of patients with alcoholic liver diseases: comparison of the situation in the seventies and at present].

作者信息

Baldini G G, Zaina A, Della Ventura G, Giacomini V, Muzio F

机构信息

Divisione Medicina Generale II, USSL 67-Regione Lombardia, Ospedale Santa Corona, Garbagnate Milanese, Milano.

出版信息

Minerva Gastroenterol Dietol. 1995 Jun;41(2):157-62.

PMID:7647138
Abstract

AIMS. 1) To evaluate the nutritional status of a group of alcohol abusers, relatively to their liver function and morphology, and 2) to compare these data with those of a previous study carried out by out team ten years ago. According to their body weight, 135 alcohol abusers were divided into three groups: normal-weight, over-weight and under-weight. The severity of their hepatopathy was defined as: 1. slight hepatopathy; 2. alcohol-induced hepatitis; 3. alcohol-induced hepatitis plus cirrhosis; 4 child A cirrhosis; 5. child B cirrhosis. RESULTS. 1. The overweight group was homogeneously distributed among the several degrees of compensated hepatopathy. 2. There was a marked reactivity to skin tests (Multitest) in patients with alcohol hepatitis without cirrhosis, independently of nutritional disorders. 3. Only decompensated cirrhosis may cause caloric-protein malnutrition; consequently, nutritional disorders due to alcohol abuse appear late and they are unlikely to play a leading role in the pathogenesis of liver disease due to alcohol abuse. Obesity, on the other hand, may facilitate the onset of liver steatosis.

摘要

目的。1)评估一组酗酒者的营养状况,及其与肝功能和形态的关系;2)将这些数据与我们团队十年前进行的一项先前研究的数据进行比较。根据体重,135名酗酒者被分为三组:正常体重、超重和体重过轻。他们肝病的严重程度定义为:1. 轻度肝病;2. 酒精性肝炎;3. 酒精性肝炎加肝硬化;4. 儿童A期肝硬化;5. 儿童B期肝硬化。结果。1. 超重组在代偿性肝病的几个程度中分布均匀。2. 无肝硬化的酒精性肝炎患者对皮肤试验(多项试验)有明显反应,与营养紊乱无关。3. 只有失代偿性肝硬化可能导致热量 - 蛋白质营养不良;因此,酗酒引起的营养紊乱出现较晚,且不太可能在酗酒所致肝病的发病机制中起主导作用。另一方面,肥胖可能促进肝脂肪变性的发生。

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