Gross Uwe
Department of Bacteriology, University Hospital of Göttingen, Kreuzbergring 57, 37075 Göttingen, Germany.
Parasitol Res. 2003 Jun;90 Supp 1:S14-8. doi: 10.1007/s00436-002-0753-x. Epub 2002 Dec 10.
Microsporidia are parasitic fungi that can infect not only arthropods and fish, but also mammals including humans. This article describes the biology of these primitive fungi and gives an overview on recent developments in therapy. Encephalitozoonspp. and the species Enterocytozoon bieneusii are most prevalent in immunocompromised patients, causing systemic disease or diarrhea. Whereas Encephalitozoon infection can usually be effectively treated with albendazole, therapeutic approaches for E. bieneusii are still difficult.
微孢子虫是一种寄生性真菌,不仅可感染节肢动物和鱼类,还能感染包括人类在内的哺乳动物。本文描述了这些原始真菌的生物学特性,并概述了其治疗方面的最新进展。脑孢子虫属物种和比氏肠微孢子虫在免疫功能低下的患者中最为常见,可导致全身性疾病或腹泻。虽然阿苯达唑通常能有效治疗脑孢子虫感染,但比氏肠微孢子虫的治疗方法仍然困难。