Hussain Shafqat, Zaman Haider, Ahmed Mukhtar
Department of Cardiac Surgery, Punjab Institute of Cardiology, Lahore.
J Coll Physicians Surg Pak. 2003 Jun;13(6):309-12.
To evaluate the safety and efficacy of intermittent aortic cross-clamping technique for myocardial preservation during coronary artery bypass grafting and to compare the results with other published series using the same technique.
An institution-based analytical study.
Study was carried out from July 1995 to December 1997 at Punjab Institute of Cardiology, Lahore.
The data of 100 consecutive patients were analyzed who had coronary artery bypass grafting without cardioplegia using intermittent aortic cross-clamping. All the patients who had emergency or concomitant major surgery, reoperations, and aortic disease with calcification were excluded from this study.
Despite minor complications there was no mortality, no rhythm disturbance or perioperative infarction. Inotropic support was needed in 8% of patients.
Our results compared favourably with other published series using the same technique. These results provide re-assurance that intermittent aortic cross-clamping provides excellent myocardial protection and operative conditions for primary coronary artery bypass. It also provides a simple and safe option for myocardial protection during coronary artery bypass grafting.
评估冠状动脉搭桥术中采用间歇性主动脉阻断技术进行心肌保护的安全性和有效性，并将结果与使用相同技术的其他已发表系列研究进行比较。
基于机构的分析性研究。
研究于1995年7月至1997年12月在拉合尔的旁遮普心脏病学研究所进行。
分析了100例连续接受冠状动脉搭桥术且未使用心脏停搏液而采用间歇性主动脉阻断的患者的数据。所有进行急诊或同期大手术、再次手术以及患有主动脉钙化疾病的患者均被排除在本研究之外。
尽管有轻微并发症，但无死亡病例，无心律失常或围手术期梗死。8%的患者需要使用正性肌力药物支持。
我们的结果与使用相同技术的其他已发表系列研究相比具有优势。这些结果再次证明，间歇性主动脉阻断为初次冠状动脉搭桥术提供了出色的心肌保护和手术条件。它也为冠状动脉搭桥术中的心肌保护提供了一种简单且安全的选择。
