Das Nagindra, Kay Vanessa J, Mahmood Tahir A
Department of Obstetrics and Gynaecology, Forth Park Hospital, Kirkcaldy, Scotland, UK.
Eur J Obstet Gynecol Reprod Biol. 2003 Jul 1;109(1):76-9. doi: 10.1016/s0301-2115(02)00486-4.
To estimate current practice of prophylactic oophorectomy at hysterectomy for benign disease and also define the role of the variables considered prior to making the decision of prophylactic oophorectomy among consultant obstetricians and gynaecologists in UK and Republic of Ireland.
A postal questionnaire was sent to all 1536 practising consultant gynaecologists in UK and Republic of Ireland. METHODS AND MAIN OUTCOMES MEASURED: Of the 809 replies received, 21% of the respondents routinely performed prophylactic oophorectomy. There was a wide regional variation; 40% consultants in Wales considered prophylactic oophorectomy compared to 16% in the Northern and Yorkshire regions. Consultants with a special interest with a more surgical bias were more likely to consider performing prophylactic oophorectomy. The majority of respondents estimated that prophylactic oophorectomy would reduce risk of ovarian cancer by up to 5%, and that following hysterectomy and ovarian conservation there was an increased risk of premature menopause.
There is a large variation and uncertainty in the practice of prophylactic oophorectomy in UK and Ireland.
评估在因良性疾病行子宫切除术时预防性卵巢切除术的当前实践情况，并明确在英国和爱尔兰的妇产科顾问医生中，在做出预防性卵巢切除术决策之前所考虑变量的作用。
向英国和爱尔兰的所有1536名执业妇产科顾问医生发送了邮寄问卷。
在收到的809份回复中，21%的受访者常规进行预防性卵巢切除术。存在广泛的地区差异；威尔士40%的顾问医生考虑进行预防性卵巢切除术，而北部和约克郡地区为16%。对手术更有偏好的专科顾问医生更有可能考虑进行预防性卵巢切除术。大多数受访者估计预防性卵巢切除术可将卵巢癌风险降低至多5%，并且子宫切除术后保留卵巢会增加过早绝经的风险。
在英国和爱尔兰，预防性卵巢切除术的实践存在很大差异和不确定性。
