Viestenz Anja, Seitz B, Küchle M, Langenbucher A, Viestenz Arne, Hofmann-Rummelt C, Naumann G O H
Augenklinik mit Poliklinik der Universität Erlangen-Nuremberg, Erlangen.
Ophthalmologe. 2003 Jun;100(6):471-5. doi: 10.1007/s00347-002-0777-8.
Results of non-mechanical corneal trepanation using the excimer laser enhance the morphological and functional results for penetrating keratoplasty. Searching for alternative laser sources we assessed the impact of an automatic laser beam control for the Er:YAG solid-state laser on the cut performance and thermal damage zone in non-mechanical corneal trepanation.
We compared the cut quality of A) a manually guided laser beam, B) a semiautomatically guided laser beam and C) a fully PC-controlled laser beam positioning system (q-switched, repetition rate 5 Hz, pulse energy 65 mJ, spot size 0.7 mm) along slit aperture masks on 28 rabbit eyes using macroscopic images and histological sections (PAS staining).
The manually guided laser beam control (A) induced the broadest thermal damage zone in the corneal stroma (19.3+/-8.7 microm) compared to the semi-automatic mode (B) (8.8+/-3.0 microm, p=0.03) and the PC-controlled laser beam control (C) (7.0+/-3.0 microm, p=0.016).
The fully automatic PC-controlled laser beam positioning system for the Er:YAG solid-state laser with a small spot size and fixed low repetition rate allows a precise laser beam guidance and a significant enhancement of the cut performance compared to a manual laser beam control via micromanipulator in experimental nonmechanical corneal trepanation.
使用准分子激光进行非机械性角膜环钻术的结果可改善穿透性角膜移植术的形态学和功能结果。在寻找替代激光源的过程中，我们评估了铒钇铝石榴石固态激光的自动激光束控制对非机械性角膜环钻术中切割性能和热损伤区的影响。
我们使用宏观图像和组织学切片（PAS染色），比较了A）手动引导激光束、B）半自动引导激光束和C）完全由计算机控制的激光束定位系统（调Q，重复频率5Hz，脉冲能量65mJ，光斑尺寸0.7mm）在28只兔眼上沿裂隙孔径掩模的切割质量。
与半自动模式（B）（8.8±3.0μm，p = 0.03）和计算机控制的激光束控制（C）（7.0±3.0μm，p = 0.016）相比，手动引导激光束控制（A）在角膜基质中引起的热损伤区最宽（19.3±8.7μm）。
与实验性非机械性角膜环钻术中通过显微操作器进行的手动激光束控制相比，具有小光斑尺寸和固定低重复频率的铒钇铝石榴石固态激光的全自动计算机控制激光束定位系统可实现精确的激光束引导并显著提高切割性能。
