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2001年萨拉热窝州居民的Q热血清学诊断

Q-fever serologic diagnostics with inhabitants of Canton of Sarajevo 2001 year.

作者信息

Beslagic Edina, Hamzic Sadeta, Puvacic Sandra, Cavaljuga-Hotic Semra

机构信息

Medical Faculty University of Sarajevo.

出版信息

Med Arh. 2003;57(2):71-4.

PMID:12822377
Abstract

Q-fever is widely spread antropoozosis caused by Coxiellae burnetti, an intracellular compulsory microbe parasite. Two characteristics of Coxiellae burnetti are of crucial importance for appearance of Q-fever, especially in the circumstances when the cause of infection remains unclear. The first one is a high resistance of Coxiellae burnetti to environment changes and the second one is a small size of the infectious dose. The clinical manifestations of Q-fever can vary, so the making of diagnosis is still based on serology, with Phase I and Phase II antibodies and the difference between the acute and the chronic form of the disease. Serologic diagnostics presents the method of choice with Q-fever (IFT) in serums of patients with clinical suspicion to Coxiellae burnetti infection. We have tested the serums of patients from Canton of Sarajevo which were coming to our laboratory from January 2001-December 2001. Out of 58 processed serums the specific IgM antibodies were found in 10 serums and specific IgG antibodies in 27 serums.

摘要

Q热是由伯纳特立克次体引起的一种广泛传播的人畜共患病,伯纳特立克次体是一种细胞内专性微生物寄生虫。伯纳特立克次体的两个特征对于Q热的出现至关重要,尤其是在感染原因不明的情况下。第一个特征是伯纳特立克次体对环境变化具有高度抗性,第二个特征是感染剂量小。Q热的临床表现可能各不相同,因此诊断仍基于血清学,依据I期和II期抗体以及疾病急性和慢性形式之间的差异。血清学诊断是疑似伯纳特立克次体感染患者血清中Q热(免疫荧光试验)的首选方法。我们检测了2001年1月至2001年12月从萨拉热窝州前来我们实验室的患者血清。在58份检测血清中,10份血清中发现了特异性IgM抗体,27份血清中发现了特异性IgG抗体。

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引用本文的文献

1
Coxiella burnetii - Pathogenic Agent of Q (Query) Fever.伯氏考克斯氏体——Q热的致病原。
Transfus Med Hemother. 2014 Feb;41(1):60-72. doi: 10.1159/000357107. Epub 2013 Dec 23.