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免疫功能低下住院患者的微孢子虫感染

[Microsporidial infections in immunocompromised hospitalized patients].

作者信息

Cisláková L, Halánová M

机构信息

Ustav epidemiológie, LF UPJS, Kosice.

出版信息

Epidemiol Mikrobiol Imunol. 2003 Apr;52(2):81-3.

Abstract

Microsporidia Encephalitozoon cuniculi, obligate intracellular sporeforming protozoan parasite infecting a wide range of vertebrate and invertebrate host, has been described as opportunistic pathogen in severely immunocompromised human host. An antibody immune response to the presence of antibodies against Encephalitozoon cuniculi was investigated serologically using indirect immunofluorescence antibody test (IFAT). Of the total number of 113 sera from immunologically compromised patients examined, 5 were positive at the titre 1:32, 5 at the titre 1:64, and 6 at the titre 1:256. From total number of positive respondent patients were 12 children and 4 adults.

摘要

微孢子虫脑炎微孢子虫,一种专性细胞内形成孢子的原生动物寄生虫,可感染多种脊椎动物和无脊椎动物宿主,在严重免疫功能低下的人类宿主中被描述为机会性病原体。使用间接免疫荧光抗体试验(IFAT)通过血清学方法研究了针对兔脑炎微孢子虫抗体存在的抗体免疫反应。在接受检查的113名免疫功能受损患者的血清总数中,5份血清滴度为1:32呈阳性,5份血清滴度为1:64呈阳性,6份血清滴度为1:256呈阳性。在呈阳性反应的患者总数中,有12名儿童和4名成人。

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