Carhan Ahmet, Ozkan Ozcan, Ozkaya Ethem
Dept. of Medical Biology, Faculty of Medicine, Yıldırım Beyazıt University, Ankara, Turkey.
Experimental Research and Application Center, Drug and Medical Devices Agency, Ankara, Turkey.
Iran J Parasitol. 2015 Apr-Jun;10(2):280-5.
As a zoonotic pathogen, Encephalitozoon cuniculi is a cause of serious disease in animals and people. The present study was to evaluate the health status examination of this seropositive animal care worker in our previous study.
Blood samples were taken from five workers. CIA test was applied to detect antibodies against E. cuniculi in blood serum. The indirect immunofluorescence antibody test was used as confirmation test. Seropositive worker had a complete medical examination.
Only one worker was found to be seropositive according to the results of the serological test. Sera positive to E. cuniculi was confirmed with IFAT and spores were detected in the urine sample of the worker. The worker was treated with albendazole.
Rabbits should be examined routinely for the presence of anti-E. cuniculi antibody. People working with laboratory animal should avoid contact with urine and faeces of infected or pay attention to personal hygiene.
兔脑炎微孢子虫作为一种人畜共患病原体,可引发人和动物的严重疾病。本研究旨在评估我们之前研究中该血清学阳性动物饲养员的健康状况检查情况。
采集了五名工作人员的血样。应用CIA试验检测血清中抗兔脑炎微孢子虫的抗体。间接免疫荧光抗体试验用作确证试验。血清学阳性的工作人员接受了全面的医学检查。
根据血清学检测结果,仅发现一名工作人员血清学阳性。通过间接免疫荧光抗体试验确证了针对兔脑炎微孢子虫的阳性血清,并在该工作人员的尿液样本中检测到了孢子。该工作人员接受了阿苯达唑治疗。
应定期检查兔子是否存在抗兔脑炎微孢子虫抗体。从事实验动物工作的人员应避免接触受感染动物的尿液和粪便,或注意个人卫生。