Alasio Teresa M, Lento Patrick A, Bottone Edward J
Department of Pathology, The Mount Sinai Hospital, New York, NY 10029, USA.
Arch Pathol Lab Med. 2003 Jul;127(7):868-71. doi: 10.5858/2003-127-868-GBOCA.
We describe a patient with extranodal non-Hodgkin lymphoma who developed systemic candidiasis after treatment with a cyclophosphamide-based chemotherapy regimen. Histologically, the fungal organisms demonstrated markedly enlarged blastoconidia with a variety of morphologic forms, mimicking other mycotic organisms, such as Cryptococcus neoformans, Blastomyces dermatitidis, and Paracoccidioides brasiliensis. The in vivo occurrence of such giant forms is rare, and when observed histologically may result in an erroneous diagnosis or a diagnosis of multiple mycotic organisms.
我们描述了一名结外非霍奇金淋巴瘤患者，其在接受基于环磷酰胺的化疗方案治疗后发生了系统性念珠菌病。组织学上，真菌生物体显示出明显增大的芽生孢子，具有多种形态，类似于其他真菌生物体，如新型隐球菌、皮炎芽生菌和巴西副球孢子菌。这种巨大形态在体内很少见，在组织学观察时可能导致错误诊断或多种真菌生物体的诊断。
