牛、马、犬和猫的胶体渗透压与血浆蛋白浓度之间的关系。

Relationship between colloid osmotic pressure and plasma protein concentration in cattle, horses, dogs, and cats.

作者信息

Thomas L A, Brown S A

机构信息

Department of Physiology and Pharmacology, College of Veterinary Medicine, University of Georgia, Athens 30602.

出版信息

Am J Vet Res. 1992 Dec;53(12):2241-4.

PMID:1282310

Abstract

The relationship between colloid osmotic pressure (COP) and protein concentration was investigated for purified proteins and plasma samples obtained from cattle, horses, dogs, and cats. At equivalent concentrations, bovine albumin exerted a COP that exceeded that of gamma-globulins by a mean factor of 4.4. Similar relationships between COP and protein were observed in the other species. Consequently, for a given total protein concentration, COP was dependent on the albumin/gamma-globulins ratio. A commonly used nomogram for estimating COP from protein concentration, the Landis-Pappenheimer equation, did not provide reliable results for plasma samples from these species.

摘要

研究了从牛、马、狗和猫身上获取的纯化蛋白质和血浆样本的胶体渗透压（COP）与蛋白质浓度之间的关系。在等效浓度下，牛血清白蛋白产生的COP比γ球蛋白的COP平均高出4.4倍。在其他物种中也观察到了COP与蛋白质之间的类似关系。因此，对于给定的总蛋白质浓度，COP取决于白蛋白/γ球蛋白的比例。一种常用的根据蛋白质浓度估算COP的列线图，即兰迪斯-帕彭海默方程，对于这些物种的血浆样本并不能提供可靠的结果。