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Molecular cloning, sequencing and alternative splicing of the acid phosphatase (Acph) gene from Drosophila virilis.

作者信息

Kitagawa Hiroko T

机构信息

Department of Chemistry, Faculty of Science, Josai University, Keyakidai 1-1, Sakado, Saitama 350-0295, Japan.

出版信息

DNA Seq. 2003 Apr;14(2):135-9. doi: 10.1080/1042517021000056961.

DOI:10.1080/1042517021000056961
PMID:12825355
Abstract

The Acph gene of Drosophila virilis was isolated from a genomic library and sequenced. The gene was organized into 6 exons interrupted by 5 introns. 5' and 3' RACE identified 3 transcripts ascribed to alternative splicing. One of them coded for 435 amino acid residues; and the others, for 403 amino acids. The shorter ones lacked 34 residues at the C-terminus end encoded by exon 6, which has been implicated in anchoring the protein to the lysosomal membrane.

摘要

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