al-Bassam Abdulrahman
Hepatogastroenterology. 2003 May-Jun;50(51):714-7.
BACKGROUND/AIMS: In spite of the well-established treatment of gastroesophageal reflux in children, the surgical management of peptic esophageal stricture remains controversial. Previous studies adopted various treatment protocols and included strictures with various degrees of severity. In this study, we selectively reviewed children with severe peptic strictures with various degrees of severity. In this study, we selectively reviewed children with severe peptic strictures treated with a specific treatment protocol of preoperative esophageal dilatation, Nissen's fundoplication and postoperative dilatation.
We reviewed medical records of all patients with severe peptic esophageal stricture treated by the above-mentioned protocol at King Khalid University Hospital, Riyadh between 1995 and 2000. Data collected included the following: presenting symptoms, methods of diagnosis and the outcome of therapy.
Ten consecutive patients who were treated for severe reflux esophageal strictures were included. Their age at surgery ranged between 2 to 12 years (mean, 5.6 years). All patients had a trial of medical treatment which failed to give any improvement of symptoms. Subsequently, all patients underwent a protocol of preoperative esophageal dilatation, Nissen's fundoplication and finally postoperative dilatation. Two patients had esophageal perforations: one by the flexible endoscope during the preoperative assessment and the other during preoperative dilatation. There were no mortalities. Eight patients showed marked improvement in their clinical symptoms and complete resolution of strictures radiologically and the remaining two showed significant improvement clinically and radiologically. The average follow-up period was 3 years (range, 1-5 years).
We conclude that preoperative dilatation, Nissen's fundoplication, and postoperative dilatation is an effective approach to treat severe pediatric peptic esophageal strictures. Other aggressive approaches described in the literature such as resection and/or replacement of the stricture are rarely indicated even for the most severe strictures.
背景/目的:尽管儿童胃食管反流的治疗方法已确立,但消化性食管狭窄的手术治疗仍存在争议。以往的研究采用了各种治疗方案,纳入了不同严重程度的狭窄病例。在本研究中,我们选择性地回顾了患有不同严重程度严重消化性狭窄的儿童。在本研究中,我们选择性地回顾了采用术前食管扩张、nissen胃底折叠术和术后扩张的特定治疗方案治疗的严重消化性狭窄儿童。
我们回顾了1995年至2000年在利雅得国王哈立德大学医院接受上述方案治疗的所有严重消化性食管狭窄患者的病历。收集的数据包括:呈现的症状、诊断方法和治疗结果。
纳入了连续10例接受严重反流性食管狭窄治疗的患者。他们手术时的年龄在2至12岁之间(平均5.6岁)。所有患者都曾尝试过药物治疗,但症状均未得到改善。随后,所有患者都接受了术前食管扩张、nissen胃底折叠术,最后进行了术后扩张。两名患者发生了食管穿孔:一名在术前评估时被柔性内窥镜穿孔,另一名在术前扩张时穿孔。无死亡病例。8例患者的临床症状明显改善,影像学上狭窄完全消失,其余2例在临床和影像学上有显著改善。平均随访期为3年(范围1至5年)。
我们得出结论,术前扩张、nissen胃底折叠术和术后扩张是治疗儿童严重消化性食管狭窄的有效方法。文献中描述的其他激进方法,如狭窄切除和/或置换,即使对于最严重的狭窄也很少适用。