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儿童食管反流性狭窄的外科治疗

Surgical management of reflux strictures of the esophagus in childhood.

作者信息

O'Neill J A, Betts J, Ziegler M M, Schnaufer L, Bishop H C, Templeton J M

出版信息

Ann Surg. 1982 Oct;196(4):453-60. doi: 10.1097/00000658-198210000-00008.

Abstract

The etiology of gastroesophageal reflux (GER) in infancy is related to developmental factors, and there is a high incidence of associated conditions such as neurologic syndromes and esophageal atresia (60%). This is different from the situation in adults. Experience with 18 consecutive children with peptic esophageal strictures is reviewed to determine if conservative surgical management is effective. Eighteen children 14 months to 13 years (mean 6.3 years) of age took an average of 3.5 years from the time of onset of symptoms of GER to develop tight strictures diagnosed by esophagography and esophagoscopy. The incidence of stricture in patients with GER was approximately 15%. Preoperative dilation or direct surgical management prior to correction of reflux is ineffective. All 18 children were managed by intraoperative dilatation, Nissen fundoplication, and guided dilatation after operation. More aggressive surgical procedures were not required nor were associated operations such as pyloroplasty; they are rarely necessary. An average three-year follow-up indicates that this conservative surgical approach is effective in the management of peptic esophageal strictures in childhood with relief of symptoms and gratifying improvement in growth.

摘要

婴儿胃食管反流(GER)的病因与发育因素有关,且常伴有神经综合征和食管闭锁等相关病症(发病率为60%)。这与成人的情况不同。回顾了连续18例患有消化性食管狭窄儿童的病例,以确定保守手术治疗是否有效。18名年龄在14个月至13岁(平均6.3岁)的儿童,从GER症状出现到经食管造影和食管镜检查确诊为严重狭窄,平均历时3.5年。GER患者中狭窄的发生率约为15%。在纠正反流之前进行术前扩张或直接手术治疗是无效的。所有18名儿童均采用术中扩张、nissen胃底折叠术及术后引导扩张进行治疗。不需要更激进的手术操作,也不需要诸如幽门成形术等相关手术;这些手术很少有必要。平均三年的随访表明,这种保守手术方法在治疗儿童消化性食管狭窄方面是有效的,可缓解症状并使生长发育得到令人满意的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/658a/1352707/45a6b945acf1/annsurg00140-0087-a.jpg

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