六种马铃薯帚顶病毒分离株外壳蛋白编码区的核苷酸序列。

Nucleotide sequences of coat protein coding regions of six potato mop-top virus isolates.

作者信息

Cerovská N, Moravec T, Rosecká P, Filigarová M, Pecenková T

机构信息

Institute of Experimental Botany, Academy of Sciences of the Czech Republic, Na Karlovce 1a, 160 00 Prague 6, the Czech Republic.

出版信息

Acta Virol. 2003;47(1):37-40.

PMID:12828342

Abstract

Coat protein (CP) coding regions of six Potato mop-top virus (PMTV) isolates from the Czech Republic and Denmark (54-10, 54-11, 54-15, 54-19, Korneta and Pacov) were sequenced. Comparison of the obtained nucleotide sequences as well as alignment of the deduced amino acid sequences were performed. The obtained results showed that the isolates from different parts of Europe seem to have highly conserved coding regions which is unexpected for a viral RNA genome known for its high mutation rate. Thus considerable differences in virulence and significant variation in biological properties of these isolates should not be attributed to CP but to some other part of the genome.

摘要

对来自捷克共和国和丹麦的六个马铃薯帚顶病毒（PMTV）分离株（54 - 10、54 - 11、54 - 15、54 - 19、Korneta和Pacov）的外壳蛋白（CP）编码区进行了测序。对获得的核苷酸序列进行了比较，并对推导的氨基酸序列进行了比对。所得结果表明，来自欧洲不同地区的分离株似乎具有高度保守的编码区，这对于以高突变率著称的病毒RNA基因组来说是出乎意料的。因此，这些分离株在毒力上的显著差异以及生物学特性的显著变化不应归因于CP，而应归因于基因组的其他部分。