McVicar John P, Albertson Timothy E, Troppmann Christoph, Kappes Janet, Perez Richard V
Department of Surgery, University of California-Davis, Sacramento, CA 95817, USA.
Transplantation. 2003 Jun 27;75(12):2128-30. doi: 10.1097/01.TP.0000069791.28896.04.
The availability of cadaveric organs is the major problem in transplantation today.
A retrospective review of donors in a single organ procurement organization (OPO) was performed. Donors were divided into three eras: before, during, and after the presence of a local lung transplant program. Lung procurement rates by OPO in the United States in 1999 and 2000 were also retrospectively reviewed.
Lung transplant rates were higher in the presence of a local lung program: 4.9% at baseline, 19.1% with a local program, and 7.1% after closure of the local lung program (P<0.01). In the United States, 12.4% of lungs available in OPOs with local lung programs are transplanted, versus 8.9% in OPOs without a local program (P<.001).
Even if donor management protocols are maintained, closure of a local lung program decreases lung recovery rates. This observation supports the importance of maintaining local programs to maximize organ recovery rates.
尸体器官的可获得性是当今移植领域的主要问题。
对单个器官获取组织（OPO）中的供体进行回顾性研究。供体被分为三个时期：当地肺移植项目开展之前、开展期间和结束之后。还回顾性研究了1999年和2000年美国各OPO的肺获取率。
当地有肺移植项目时肺移植率更高：基线时为4.9%，有当地项目时为19.1%，当地肺移植项目结束后为7.1%（P<0.01）。在美国，有当地肺移植项目的OPO中12.4%的可用肺被移植，而没有当地项目的OPO中这一比例为8.9%（P<0.001）。
即使维持供体管理方案不变，当地肺移植项目的结束仍会降低肺的获取率。这一观察结果支持了维持当地项目以最大化器官获取率的重要性。
