Evidence-based care for the neutropenic patient with leukemia.

OBJECTIVES

To provide an overview of risk factors for increased severity of infection, and a summary of neutropenic care guidelines based on the scientific literature.

DATA SOURCES

Research studies, review articles, book chapters.

CONCLUSION

Neutropenia is one of the most common and clinically significant toxicities of therapy for patients with leukemia. The risk of infection is extremely high and is associated with significant morbidity and mortality. Specific risk factors for serious or life-threatening infection must be identified in this patient population and abrogated when possible.

IMPLICATIONS FOR NURSING PRACTICE

Implementation of evidence-based preventive and management strategies for patients with neutropenia can optimize patient outcomes. Internalization of these concepts into the nursing care we provide to patients with leukemia exemplifies best practice.