Gencosmanoglu Rasim, Sen-Oran Ebru, Kurtkaya-Yapicier Ozlem, Tozun Nurdan
Department of Gastrointestinal Surgery, Marmara University Institute of Gastroenterology, Istanbul, Turkey.
BMC Gastroenterol. 2003 Jun 27;3:16. doi: 10.1186/1471-230X-3-16.
Hyperplastic polyps are the most common polypoid lesions of the stomach. Rarely, they cause gastric outlet obstruction by prolapsing through the pyloric channel, when they arise in the prepyloric antrum.
A 62-year-old woman presented with intermittent nausea and vomiting of 4 months duration. Upper gastrointestinal endoscopy revealed a 30 mm prepyloric sessile polyp causing intermittent gastric outlet obstruction. Following submucosal injection of diluted adrenaline solution, the polyp was removed with a snare. Multiple biopsies were taken from the greater curvature of the antrum and the corpus. Rapid urease test for Helicobacter pylori yielded a negative result. Histopathologic examination showed a hyperplastic polyp without any evidence of malignancy. Biopsies of the antrum and the corpus revealed gastritis with neither atrophic changes nor Helicobacter pylori infection. Follow-up endoscopy after a 12-week course of proton pomp inhibitor therapy showed a complete healing without any remnant tissue at the polypectomy site. The patient has been symptom-free during 8 months of follow-up.
Symptomatic gastric polyps should be removed preferentially when they are detected at the initial diagnostic endoscopy. Polypectomy not only provides tissue to determine the exact histopathologic type of the polyp, but also achieves radical treatment.
增生性息肉是胃最常见的息肉样病变。当它们起源于幽门窦时,很少会通过幽门管脱垂导致胃出口梗阻。
一名62岁女性,出现持续4个月的间歇性恶心和呕吐。上消化道内镜检查发现一个30毫米的幽门部无蒂息肉,导致间歇性胃出口梗阻。在黏膜下注射稀释的肾上腺素溶液后,用圈套器切除息肉。从胃窦大弯和胃体取了多个活检样本。幽门螺杆菌快速尿素酶试验结果为阴性。组织病理学检查显示为增生性息肉,无任何恶性证据。胃窦和胃体的活检显示为胃炎,无萎缩性改变,也无幽门螺杆菌感染。在进行12周质子泵抑制剂治疗后进行的随访内镜检查显示完全愈合,息肉切除部位无任何残留组织。在8个月的随访期间,患者无症状。
有症状的胃息肉在初次诊断性内镜检查时被发现应优先切除。息肉切除术不仅能提供组织以确定息肉的确切组织病理学类型,还能实现根治性治疗。