Division of Gastroenterology, Kubo Hospital, 1-1-19 Uchibori, Imabari 799-2116, Japan.
Gastroenterol Res Pract. 2009;2009:845260. doi: 10.1155/2009/845260. Epub 2009 Dec 15.
A case of gastric hyperplastic polyp with proliferation of xanthoma cells is reported. The patient was a 69-year-old man who visited our hospital for further evaluation of gastric polyps. Endoscopic examination of the upper digestive tract revealed multiple hyperplastic polyps in the gastric antrum. There was a pedunculated polyp with whitish yellow granules, 7 mm in diameter, arising from the greater curvature of the antrum. Magnification narrow-band imaging endoscopy (GIF-H260Z, Olympus) revealed long microcapillaries in the polyp but did not reveal disappearance of the mucosal microstructure or irregular branched capillaries. Endoscopic mucosal resection (EMR) was performed. Histological examination of the specimen revealed the lengthened gastric foveolae in the superficial portion and tight sheet of foamy histiocytes in the lamina propria. Diagnosis of gastric hyperplastic polyp with proliferation of xanthoma cells was made. There was no evidence of malignancy. It is necessary to know that a gastric hyperplastic polyp may associate with gastric xanthoma, although such association is very rare.
本文报告了一例胃增生性息肉伴黄色瘤细胞增生。患者为 69 岁男性，因胃息肉就诊于我院。上消化道内镜检查发现胃窦部多发增生性息肉。胃窦大弯可见一直径 7mm 的带蒂息肉，表面附有黄白色颗粒。放大窄带成像内镜（GIF-H260Z，Olympus）显示息肉内有长微毛细血管，但未发现黏膜微观结构消失或不规则分支毛细血管。行内镜下黏膜切除术（EMR）。标本组织学检查显示，浅层胃小凹拉长，固有层有紧密的泡沫状组织细胞层。诊断为胃增生性息肉伴黄色瘤细胞增生。无恶性证据。需要知道的是，胃增生性息肉可能与胃黄色瘤相关，尽管这种关联非常罕见。
