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颈总动脉支架置入术的现状

Current status in cervical carotid artery stent placement.

作者信息

Wholey M H, Wholey M

机构信息

Department of Cardiovascular and Interventional Radiology, University of Texas, Health Science Center at San Antonio, 78284, USA.

出版信息

J Cardiovasc Surg (Torino). 2003 Jun;44(3):331-9.

Abstract

Aim of this paper is to provide background information and the latest developments and studies pertaining to carotid artery stent placement in the treatment of carotid artery occlusive disease. A review of current literature combined with personal experience in the field of carotid stenting is presented. Endovascular stent placement for carotid artery occlusive disease is evolving from its initial controversial position to that of an alternative treatment of extracranial carotid artery disease. The high technical success (98-99%) as well as the relatively few complications makes carotid stenting a substitute for carotid endarterectomy for symptomatic patients and especially those with high medical comorbidities. With the advent of distal embolic protection, the complication rates for carotid stenting have decreased by approximately 50% to 2-4% for most major centers. Hence, with improved technology, carotid stenting is becoming an option for asymptomatic patients, especially those with high surgical risk. Early results for patency and neurological follow-up have also been encouraging. When we first began performing carotid stenting in 1995, we used a mixture of peripheral and coronary techniques. As stent design, guide catheters and cerebral protection devices have become dedicated and sophisticated, the technical success, patency and complication rates have improved. Carotid stenting will increase in application in the future especially among high surgical-risk patients with symptomatic and asymptomatic carotid occlusive disease.

摘要

本文旨在提供有关颈动脉支架置入术治疗颈动脉闭塞性疾病的背景信息以及最新进展和研究情况。本文结合了颈动脉支架置入领域的个人经验对当前文献进行了综述。用于治疗颈动脉闭塞性疾病的血管内支架置入术正从最初备受争议的地位逐渐发展成为颅外颈动脉疾病的一种替代治疗方法。较高的技术成功率(98 - 99%)以及相对较少的并发症使得颈动脉支架置入术成为有症状患者,尤其是那些合并多种严重内科疾病患者的颈动脉内膜切除术替代方案。随着远端栓子保护装置的出现,大多数主要中心的颈动脉支架置入术并发症发生率已降低约50%,降至2 - 4%。因此,随着技术的改进,颈动脉支架置入术正成为无症状患者的一种选择,尤其是那些手术风险高的患者。通畅率和神经功能随访的早期结果也令人鼓舞。1995年我们刚开始开展颈动脉支架置入术时,使用的是外周和冠状动脉技术的混合方法。随着支架设计、引导导管和脑保护装置变得更加专用和精密,技术成功率、通畅率和并发症发生率都有所提高。未来,颈动脉支架置入术的应用将会增加,尤其是在有症状和无症状颈动脉闭塞性疾病的高手术风险患者中。

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