粘质沙雷氏菌O2和O3血清群参考菌株脂多糖中一种中性聚糖的结构

Structure of a neutral glycan from the lipopolysaccharides of reference strains for Serratia marcescens serogroups O2 and O3.

作者信息

Oxley D, Wilkinson S G

机构信息

School of Chemistry, University of Hull, UK.

出版信息

FEMS Microbiol Lett. 1992 Dec 1;78(2-3):209-12. doi: 10.1016/0378-1097(92)90027-l.

DOI:10.1016/0378-1097(92)90027-l

PMID:1283379

Abstract

Serogroups O2 and O3 of Serratia marcescens are differentiated by acidic glycans present in the aqueous phase when lipopolysaccharides are extracted from the reference strains by the aqueous-phenol method. The phenolic phases of these extracts from both strains also contain lipopolysaccharides, from which the same neutral glycan is released on milk acid hydrolysis. The neutral glycan has the disaccharide repeating-unit shown, and accounts for the cross-reactions between the two serogroups and also with serogroup O21: --> 4)-alpha-D-GlcpNAc-(1-->4)-beta-D-ManpNAc-(1--.

摘要

粘质沙雷氏菌的O2和O3血清群可通过水相中的酸性聚糖来区分，当采用水-酚法从参考菌株中提取脂多糖时会出现这种情况。这两种菌株提取物的酚相也含有脂多糖，在乳酸水解时会从中释放出相同的中性聚糖。该中性聚糖具有所示的二糖重复单元，这解释了两个血清群之间以及与O21血清群之间的交叉反应：--> 4)-α-D-葡萄糖胺-(1-->4)-β-D-甘露糖胺-(1--。