Iwai Yoshiyasu, Yamanaka Kazuhiro, Morikawa Toshie, Ishiguro Tomoya, Honda Yuji, Matsuzaka Yasuhiro, Komiyama Masaki, Yasui Toshihiro
Department of Neurosurgery, Osaka City General Hospital, 2-13-22 Miyakojima-handohri, Miyakojima-ku, Osaka-city, Osaka 534-0021, Japan.
No Shinkei Geka. 2003 Jun;31(6):649-55.
We evaluated the surgical treatment results of parasellar meningiomas in the era of radiosurgery. We treated 24 patients of parasellar meningiomas surgically. The median age was 60 yrs (ranging from 29 to 82 yrs). The most common tumor location was the sphenoid ridge in 12 patients and the tuberculum sellae in 7 patients. The pterional approach using fronto-temporal craniotomy was performed for all patients. The residual or recurrent tumors were treated by gamma knife radiosurgery (GKS). We are able to follow up these cases for a median of 3.8 yrs (ranging from 1 to 8 yrs) after the operations. The radicality of tumor resection was Simpson grade II in 13 patients (54%), grade III in 3 patients (13%) and grade IV in 7 patients (33%). Clinical improvement was achieved in 81% of the patients. Of the patients who had visual disturbance preoperatively, 8 patients (73%) showed improvement, but 3 patients suffered deterioration postoperatively. None of the patients died. One patient suffered transient memory disturbance and one patient suffered mild facial numbness postoperatively. Boost radiosurgery for the residual tumors was performed for six patients and tumor growth control was able to be achieved in all patients, with a median of 3.1 years follow-up period (ranging from 0.5 to 6 yrs). Five patients with tumor regrowth or recurrence were treated by GKS. We recommend fronto-temporal craniotomy with nonradical resection for parasellar meningiomas and radiosurgery for residual and recurrent tumors. This strategy will achieve good functional outcome with long-term tumor growth control.
我们评估了放射外科时代鞍旁脑膜瘤的手术治疗结果。我们对24例鞍旁脑膜瘤患者进行了手术治疗。中位年龄为60岁(范围为29至82岁)。最常见的肿瘤位置是蝶骨嵴,有12例患者;鞍结节,有7例患者。所有患者均采用额颞开颅翼点入路。残留或复发性肿瘤采用伽玛刀放射外科治疗(GKS)。术后我们能够对这些病例进行中位时间为3.8年(范围为1至8年)的随访。肿瘤切除的彻底性为Simpson II级的有13例患者(54%),III级的有3例患者(13%),IV级的有7例患者(33%)。81%的患者临床症状得到改善。术前有视力障碍的患者中,8例(73%)症状改善,但3例术后病情恶化。无患者死亡。1例患者术后出现短暂性记忆障碍,1例患者术后出现轻度面部麻木。对6例残留肿瘤患者进行了辅助放射外科治疗,所有患者均实现了肿瘤生长控制,中位随访期为3.1年(范围为0.5至6年)。5例肿瘤复发或再生长的患者接受了GKS治疗。我们推荐对鞍旁脑膜瘤采用额颞开颅非根治性切除,对残留和复发性肿瘤采用放射外科治疗。该策略将实现良好的功能预后并长期控制肿瘤生长。