Wang C-H, Lin S-M, Chen Y, Tseng S-H
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
Acta Neurochir (Wien). 2003 Jun;145(6):505-8; discussion 508. doi: 10.1007/s00701-003-0041-2.
Cavernomas are rarely located in the third ventricle, hypothalamus, or thalamus. In this report, we present our experience managing a patient with three cavernomas, one each in the floor of the third ventricle, hypothalamus, and left thalamus.
This 62-year-old woman had had an unsteady gait and weakness of both legs for six months. Magnetic resonance imaging (MRI) revealed multiple intracranial tumours in the third ventricle, hypothalamus, and left thalamus. The third ventricle tumour was found to be a cavernoma by intra-operative endoscopic examination and then was excised via a transcortical, transventricular approach. Pathology revealed a cavernoma. The other two tumours were assumed to be cavernomas because of their MRI features. Three days after surgery, the patient developed right hemiparesis and disturbance of consciousness. Computed tomography revealed a left thalamic haemorrhage. After conservative treatment, her conscious level gradually recovered and she could walk with support seven months after surgery.
Our experience with this rare case of multiple, deep-seated cavernomas suggests that management of such patients requires specific consideration of the clinical manifestations, location, size, and previous bleeding history.
海绵状血管瘤很少位于第三脑室、下丘脑或丘脑。在本报告中,我们介绍了我们治疗一名患有三个海绵状血管瘤患者的经验,这三个血管瘤分别位于第三脑室底部、下丘脑和左侧丘脑。
这名62岁女性出现步态不稳和双腿无力已有6个月。磁共振成像(MRI)显示第三脑室、下丘脑和左侧丘脑有多个颅内肿瘤。术中内镜检查发现第三脑室肿瘤为海绵状血管瘤,随后通过经皮质、经脑室入路将其切除。病理检查显示为海绵状血管瘤。由于另外两个肿瘤的MRI特征,推测它们也是海绵状血管瘤。术后三天,患者出现右侧偏瘫和意识障碍。计算机断层扫描显示左侧丘脑出血。经过保守治疗,她的意识水平逐渐恢复,术后七个月在有人搀扶的情况下能够行走。
我们对这例罕见的多发深部海绵状血管瘤病例的经验表明,对此类患者的治疗需要特别考虑临床表现、位置、大小和既往出血史。