Roux Christian
Centre d'Evaluation des Maladies Osseuses, Institut de Rhumatologie, Hôpital Cochin, 27, rue du Faubourg Saint-Jacques, 75014 Paris, France.
Med Sci (Paris). 2003 Feb;19(2):231-8. doi: 10.1051/medsci/2003192231.
Measurement of bone mineral density (BMD) using dual energy X-ray absorptiometry is the basis of the definition of osteoporosis. Accuracy, precision and sensitivity of the method are good enough for clinical use. Prospective studies have shown that there is a gradient of risk between the decrease in BMD, related to age and hormonal insufficiency, and the increase in the incidence of fracture. Thus, therapeutic decision is based on both BMD and clinical risk factors that contribute to fracture risk.
使用双能X线吸收法测量骨矿物质密度(BMD)是骨质疏松症定义的基础。该方法的准确性、精密度和灵敏度足以用于临床。前瞻性研究表明,与年龄和激素不足相关的BMD降低与骨折发生率增加之间存在风险梯度。因此,治疗决策基于BMD和导致骨折风险的临床风险因素。