Purcell S, Sham P C
Social, Genetic & Developmental Research Centre, Institute of Psychiatry, London SE5 8AF, UK.
Behav Genet. 2003 May;33(3):271-8. doi: 10.1023/a:1023494408079.
In this research note, DeFries-Fulker (DF) regression analysis is reframed in model-fitting terms, where an individual's expected score is modeled as a function of their co-twin's proband status. This more flexible implementation of the DF model allows DZ-O twins to be incorporated in a sex-limitation model. Brief simulation results are presented along with the Mx scripts used.
在本研究报告中,德弗里斯-富尔克(DF)回归分析是以模型拟合的方式重新构建的,其中个体的预期分数被建模为其同卵双胞胎的先证者状态的函数。DF模型的这种更灵活的实现方式允许将异卵同性双胞胎纳入性别限制模型。同时还给出了简要的模拟结果以及所使用的Mx脚本。