Trushinskaia G N, Simonov V I, Makarova N E, Nosik D N, Kushch A A, Gibadulin R A
Vestn Ross Akad Med Nauk. 1992(9-10):43-7.
The paper describes the enzyme immunoassay system for detection of human immunodeficiency virus antigens, which is based on the use of rabbit anti-HIV antibodies and monoclonal antibodies to HIV-1 gene proteins gag. The system may be useful in the examination of laboratory and clinical samples to reveal both free and conjugated antigens in the composition of immune complexes. The sensitivity of the assay system under development is 0.5 ng/ml at 100% specificity.
本文描述了一种用于检测人类免疫缺陷病毒抗原的酶免疫测定系统，该系统基于使用兔抗HIV抗体和针对HIV-1基因蛋白gag的单克隆抗体。该系统可用于检测实验室和临床样本，以揭示免疫复合物组成中的游离抗原和结合抗原。正在开发的测定系统在100%特异性下的灵敏度为0.5 ng/ml。
