Baykal Cem, Sargon Mustafa F, Esinler Ibrahim, Onderoğlu Selda, Onderoğlu Lütfü
SSK Ankara Maternity Hospital, Ankara, Turkey.
Arch Gynecol Obstet. 2004 Sep;270(2):99-103. doi: 10.1007/s00404-003-0511-z. Epub 2003 Jun 28.
The aim of this study is to investigate the ultra structural difference of placentas in IUGR fetuses that were all found to have abnormal umbilical artery Doppler waveforms.
Nine placentas from 7 IUGR fetuses and 2 from healthy normal fetuses were evaluated by scanning electron microscopy.
All of the placentas of IUGR fetuses who had abnormal umbilical artery Doppler flow antenatally were found to have a prominent increase in the amount of total blood vessels; these aberrant blood vessels had a very tortuous course and they showed increased branching when compared with placentas from uncomplicated term pregnancies.
Our study showed that there is a clear difference in vascular ultra structure of the placentas of pregnancies with fetal growth restriction selected by abnormal umbilical artery Doppler flow test. IUGR seems to be a problem due to placental vascular insufficiency.
本研究旨在调查所有脐动脉多普勒波形异常的小于胎龄儿（IUGR）胎儿胎盘的超微结构差异。
通过扫描电子显微镜对来自7例IUGR胎儿的9个胎盘和2例健康正常胎儿的胎盘进行评估。
产前脐动脉多普勒血流异常的IUGR胎儿的所有胎盘均显示总血管数量显著增加；这些异常血管走行非常曲折，与足月正常妊娠胎盘相比，分支增多。
我们的研究表明，通过异常脐动脉多普勒血流试验选择的胎儿生长受限妊娠胎盘的血管超微结构存在明显差异。IUGR似乎是由于胎盘血管功能不全所致。
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